Referencias Bibliográficas sobre Probióticos para Niños

(1) World Gastroenterology Organisation, 2023.  Probióticos y prebióticos. Febrero de 2023

(2) Guarino A, Ashkenazi S, Gendrel D, Lo Vecchio A, Shamir R, Szajewska H; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition; European Society for Pediatric Infectious Diseases. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition/European Society for Pediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe: update 2014. J Pediatr Gastroenterol Nutr. 2014 Jul;59(1):132-52. doi: 10.1097/MPG.0000000000000375. PMID: 24739189.

(3) Corrêa NB, Péret Filho LA, Penna FJ, Lima FM, Nicoli JR. A randomized formula controlled trial of Bifidobacterium lactis and Streptococcus thermophilus for prevention of antibiotic-associated diarrhea in infants. J Clin Gastroenterol. 2005;39(5):385-389. doi:10.1097/01.mcg.0000159217.47419.5b

(4) Lönnermark E, Friman V, Lappas G, Sandberg T, Berggren A, Adlerberth I. Intake of Lactobacillus plantarum reduces certain gastrointestinal symptoms during treatment with antibiotics. J Clin Gastroenterol. 2010;44(2):106-112. doi:10.1097/MCG.0b013e3181b2683f

(5) Beghetti I, Panizza D, Lenzi J, Gori D, Martini S, Corvaglia L, Aceti A. Probiotics for Preventing Necrotizing Enterocolitis in Preterm Infants: A Network Meta-Analysis. Nutrients. 2021 Jan 9;13(1):192. doi: 10.3390/nu13010192. PMID: 33435456; PMCID: PMC7827781.

(6) Sur D, Manna B, Niyogi SK, Ramamurthy T, Palit A, Nomoto K, Takahashi T, Shima T, Tsuji H, Kurakawa T, Takeda Y, Nair GB, Bhattacharya SK. Role of probiotic in preventing acute diarrhoea in children: a community-based, randomized, double-blind placebo-controlled field trial in an urban slum. Epidemiol Infect. 2011 Jun;139(6):919-26. doi: 10.1017/S0950268810001780. Epub 2010 Jul 30. PMID: 20670468.

(7) Beausoleil M, Fortier N, Guénette S, L'ecuyer A, Savoie M, Franco M, Lachaine J, Weiss K. Effect of a fermented milk combining Lactobacillus acidophilus Cl1285 and Lactobacillus casei in the prevention of antibiotic-associated diarrhea: a randomized, double-blind, placebo-controlled trial. Can J Gastroenterol. 2007 Nov;21(11):732-6. doi: 10.1155/2007/720205. PMID: 18026577; PMCID: PMC2658588.

(8) Janvier A, Malo J, Barrington KJ. Cohort study of probiotics in a North American neonatal intensive care unit. J Pediatr. 2014 May;164(5):980-5. doi: 10.1016/j.jpeds.2013.11.025. Epub 2014 Jan 7. Erratum in: J Pediatr. 2014 Jun;164(6):1503. PMID: 24411521.

(9) Martoni CJ, Srivastava S, Leyer GJ. Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial. Nutrients. 2020 Jan 30;12(2):363. doi: 10.3390/nu12020363. PMID: 32019158; PMCID: PMC7071206.

(10) Jirapinyo P, Densupsoontorn N, Thamonsiri N, Wongarn R. Prevention of antibiotic-associated diarrhea in infants by probiotics. J Med Assoc Thai. 2002 Aug;85 Suppl 2:S739-42. PMID: 12403254.

(11) Engelbrektson A, Korzenik JR, Pittler A, Sanders ME, Klaenhammer TR, Leyer G, Kitts CL. Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy. J Med Microbiol. 2009 May;58(Pt 5):663-670. doi: 10.1099/jmm.0.47615-0. PMID: 19369530.

(12) Turner RB, Woodfolk JA, Borish L, Steinke JW, Patrie JT, Muehling LM, Lahtinen S, Lehtinen MJ. Effect of probiotic on innate inflammatory response and viral shedding in experimental rhinovirus infection - a randomised controlled trial. Benef Microbes. 2017 Apr 26;8(2):207-215. doi: 10.3920/BM2016.0160. Epub 2017 Mar 27. PMID: 28343401; PMCID: PMC5797652.

(13) Szymański H, Armańska M, Kowalska-Duplaga K, Szajewska H. Bifidobacterium longum PL03, Lactobacillus rhamnosus KL53A, and Lactobacillus plantarum PL02 in the prevention of antibiotic-associated diarrhea in children: a randomized controlled pilot trial. Digestion. 2008;78(1):13-7. doi: 10.1159/000151300. Epub 2008 Aug 14. PMID: 18701826.

(14) Drouault-Holowacz S, Bieuvelet S, Burckel A, Cazaubiel M, Dray X, Marteau P. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome. Gastroenterol Clin Biol. 2008 Feb;32(2):147-52. doi: 10.1016/j.gcb.2007.06.001. Epub 2008 Mar 4. PMID: 18387426.

(15) Cazaubiel, M., & Bieuvelet, S. (2008). A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome. Gastroentérologie Clinique Et Biologique.

(16) O’Brien, C.E., Meier, A.K., Cernioglo, K. et al. Early probiotic supplementation with B. infantis in breastfed infants leads to persistent colonization at 1 year. Pediatr Res 91, 627–636 (2022). https://doi.org/10.1038/s41390-020-01350-0

(17) Maldonado J, Cañabate F, Sempere L, et al. Human milk probiotic Lactobacillus fermentum CECT5716 reduces the incidence of gastrointestinal and upper respiratory tract infections in infants [published correction appears in J Pediatr Gastroenterol Nutr. 2012 Apr;54(4):571]. J Pediatr Gastroenterol Nutr. 2012;54(1):55-61. doi:10.1097/MPG.0b013e3182333f18

(18) Ouwehand AC, DongLian C, Weijian X, Stewart M, Ni J, Stewart T, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: A randomized dose response study. Vaccine. 2014;32:458–463. doi: 10.1016/j.vaccine.2013.11.053. 

(19) Nagpal, Ravinder & Kaur, Varinder & Kumar, Manoj & Marotta, Francesco. (2013). Effect of Aloe vera juice on growth & activities of Lactobacilli in-vitro. Acta bio-medica: Atenei Parmensis. 83. 183-188.

(20) Cuvas, Ruth & Julio, Montañez & Contreras-Esquivel, Juan & Mario, Cruz & Mussatto, Solange & Belmares, Ruth. (2016). Aloe vera and Probiotics: A New Alternative to Symbiotic Functional Foods. Annual Research & Review in Biology. 9. 1-11. 10.9734/ARRB/2016/22622.

(21) Vanderhoof JA, Whitney DB, Antonson DL, Hanner TL, Lupo JV, Young RJ. Lactobacillus GG in the prevention of antibiotic-associated diarrhea in children. J Pediatr. 1999;135(5):564-568. doi:10.1016/s0022-3476(99)70053-3

(22) Cazzola M, Pham-Thi N, Kerihuel JC, Durand H, Bohbot S. Efficacy of a synbiotic supplementation in the prevention of common winter diseases in children: a randomized, double-blind, placebo-controlled pilot study. Ther Adv Respir Dis. 2010;4(5):271-278. doi:10.1177/1753465810379010

(23) Ouwehand AC, Isolauri E, He F, Hashimoto H, Benno Y, Salminen S. Differences in Bifidobacterium flora composition in allergic and healthy infants. J Allergy Clin Immunol. 2001;108(1):144-145. doi:10.1067/mai.2001.115754

(24) Acidophilus Milk Products: A Review of Potential Benefits to Consumers Gilliland S.E.(1989) Journal of Dairy Science, 72 (10) , pp. 2483-2494.

(25) Nocerino R, De Filippis F, Cecere G, Marino A, Micillo M, Di Scala C, de Caro C, Calignano A, Bruno C, Paparo L, Iannicelli AM, Cosenza L, Maddalena Y, Della Gatta G, Coppola S, Carucci L, Ercolini D, Berni Canani R. The therapeutic efficacy of Bifidobacterium animalis subsp. lactis BB-12® in infant colic: A randomised, double blind, placebo-controlled trial. Aliment Pharmacol Ther. 2020 Jan;51(1):110-120. doi: 10.1111/apt.15561. Epub 2019 Dec 3. PMID: 31797399; PMCID: PMC6973258.

(26) Chen K, Zhang G, Xie H, You L, Li H, Zhang Y, Du C, Xu S, Melsaether C, Yuan S. Efficacy of Bifidobacterium animalis subsp. lactis, BB-12® on infant colic - a randomised, double-blinded, placebo-controlled study. Benef Microbes. 2021 Nov 16;12(6):531-540. doi: 10.3920/BM2020.0233. Epub 2021 Sep 22. PMID: 34550055.

(27) Ohashi Y, Sumitani K, Tokunaga M, Ishihara N, Okubo T, Fujisawa T. Consumption of partially hydrolysed guar gum stimulates Bifidobacteria and butyrate-producing bacteria in the human large intestine. Benef Microbes. 2015;6(4):451-5. doi: 10.3920/BM2014.0118. Epub 2015 Feb 12. PMID: 25519526.

(28) Yasukawa Z, Inoue R, Ozeki M, Okubo T, Takagi T, Honda A, Naito Y. Effect of Repeated Consumption of Partially Hydrolyzed Guar Gum on Fecal Characteristics and Gut Microbiota: A Randomized, Double-Blind, Placebo-Controlled, and Parallel-Group Clinical Trial. Nutrients. 2019 Sep 10;11(9):2170. doi: 10.3390/nu11092170. PMID: 31509971; PMCID: PMC6769658.

(29) Kalman, D.S., Schwartz, H.I., Alvarez, P. et al. A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms. BMC Gastroenterol 9, 85 (2009). https://doi.org/10.1186/1471-230X-9-85

(30) Rogha M, Esfahani MZ, Zargarzadeh AH. The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial. Gastroenterol Hepatol Bed Bench. 2014;7(3):156-163.

(31) Anaya-Loyola MA, Enciso-Moreno JA, Lopez-Ramos JE, Garcia-Marin G, Orozco Alvarez MY, Vega-Garcai AM, Mosqueda J, Garcia-Gutierrez DG, Keller D, Perez-Ramirez IF. Bacillus coagulans GBI-30, 6086 decreases upper respiratory and gastrointestinal tract symptoms in healthy Mexican scholar-aged children by modulating immune-related proteins. (2019) 

(32) Cui, X and Wure, G. 2003. The treatment of 62 cases of rotavirus gastroenteritis by Biostime probiotics. Chin J Gen Med 5:53-54.

(33) Jiang X. 2008. Clinical evaluation of Biostime in the treatment of children with persistent diarrhea. The 6th Chin National Conf on Pediatr Microecol 142-145.

(34) Chen L, Ouyang L-J, Liao W-J, Zhang W-H. 2007. Mucous membrane immunity enhanced by taking Biostime probiotics. Chin J Ecol 19:137-141.

(35) Cazzola M, Pham-Thi N, Kerihuel JC, Durand H, Bohbot S. 2010b. Efficacy of a synbiotic supplementation in the prevention of common winter diseases in children: a randomized, double-blind, placebo-controlled pilot study. Ther Adv. Respir Dis 4:271-278.

(36) Tremblay A, Xu X, Colee J, Tompkins TA. Efficacy of a Multi-Strain Probiotic Formulation in Pediatric Populations: A Comprehensive Review of Clinical Studies. Nutrients. 2021 Jun 1;13(6):1908. doi: 10.3390/nu13061908. PMID: 34206098; PMCID: PMC8226750.

(37) Kołodziej M, Szajewska H. Lactobacillus reuteri DSM 17938 in the prevention of antibiotic-associated diarrhoea in children: protocol of a randomised controlled trial. BMJ Open. 2017;7(1): e013928. DOI: 10.1136/bmjopen-2016-013928

(38) Francavilla, R., Lionetti, E., Castellaneta, S., Ciruzzi, F., Indrio, F., Masciale, A., Fontana, C., La Rosa, M.M., Cavallo, L. and Francavilla, A., 2012. Randomised clinical trial: Lactobacillus reuteri DSM 17938 vs. placebo in children with acute diarrhoea – a double-blind study. Alimentary Pharmacology and Therapeutics 36: 363-369.

(39). Dinleyici EC, Dalgic N, Guven S, et al. Lactobacillus reuteri DSM 17938 shortens acute infectious diarrhea in a pediatric outpatient setting. J Pediatr (Rio J). 2015;91:392-396.

(40) Urbanska M, Szajewska H. The efficacy of Lactobacillus reuteri DSM 17938 in infants and children: a review of the current evidence. Eur J Pediatr. 2014;173:1327-1337.

(41) Savino F. et al., (2015), ‘Preventive effects of oral probiotic on infantile colic: a prospective, randomised, blinded, controlled trial using Lactobacillus reuteri DSM 17938’. Benef. Microbes, 6(3):245-251, ePub 8 Dec. 2014.

(42) Weizman Z, Abu-Abed J, Binsztok M. Lactobacillus reuteri DSM 17938 for the Management of Functional Abdominal Pain in Childhood: A Randomized, Double-Blind, Placebo-Controlled Trial. J Pediatr. 2016;174:160-164.e1. doi:10.1016/j.jpeds.2016.04.003

(43) Kawahara T, Makizaki Y, Oikawa Y, et al. Oral administration of Bifidobacterium bifidum G9-1 alleviates rotavirus gastroenteritis through regulation of intestinal homeostasis by inducing mucosal protective factors. PLoS One. 2017;12(3):e0173979. Published 2017 Mar 27. doi:10.1371/journal.pone.0173979

(44) M. Margreiter, K. Ludl, W. Phleps and S.T. Kaehler.Therapeutic value of a Lactobacillus gasseri and Bifidobacterium longum fixed bacterium combination in acute diarrhea: a randomized, double-blind, controlled clinical trial. 2006; 44: 207-215. doi: 10.5414/CPP44207.

(45) Jennifer C Dennis-Wall, Tyler Culpepper, Carmelo Nieves, Jr., Cassie C Rowe, Alyssa M Burns, Carley T Rusch, Ashton Federico, Maria Ukhanova, Sheldon Waugh, Volker Mai, Mary C Christman, Bobbi Langkamp-Henken, Probiotics (Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2) improve rhinoconjunctivitis-specific quality of life in individuals with seasonal allergies: a double-blind, placebo-controlled, randomized trial, The American Journal of Clinical Nutrition, Volume 105, Issue 3, March 2017, Pages 758–767,

(46) Mack D.R. et al., (2003), ‘Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro’. Gut, 52:827-33.

(47) Thijssen A.Y. et al., (2011), ‘A randomized, placebo-controlled double blind study to assess the efficacy of a probiotic dairy product containing Lactobacillus casei Shirota on symptoms of irritable bowel syndrome’. Gastroenterology, 140(5,S1):S609.

(48) Koebnick C. et al., (2003), ‘Probiotic beverage containing Lactobacillus casei Shirota improves gastrointestinal symptoms in patients with chronic constipation’. Canadian Journal of Gastroenterology, 17(11):655 – 659.

(49) Hickson M, D’Souza AL, Muthu N, et al. Use of probiotic Lactobacilluspreparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ. 2007;335:80.

(50) Cionci N e et al. (2018). Therapeutic Microbiology: The role of Bifidobacterium breve as food supplement for the prevention/treatment of paediatric diseases. Nutrients , 10 (11): 1723 .

Eduardo Santos de Paz

Farmacéutico - U. Complutense - Madrid Diplomado en Óptica Oftálmica y Optometría - Univ. de Barcelona

Subir