The composition of our intestinal microbiota and its activity as a microbial community is closely related to our health and well-being. The effects of probiotic supplements take place at the gastrointestinal level since that is where they colonize the microorganisms.
A wide variety of probiotics of different composition and concentration of microorganisms can be found on the market. Let’s look at some of them.
Align Probiotic – Bacillus coagulans – DualBiotic Gummies
Align Probiotic DualBiotic is a pleasant-tasting gummy containing 1 billion cfu of LactoSpore ®, a registered trademark containing a single probiotic species: Bacillus coagulans. It is a product with several thousand evaluations, all very positive, made by its consumers
The bacterium it contains, Bacillus coagulans, is common in the microbiota of the human gastrointestinal tract and plays a crucial role in maintaining the stability and diversity of the microbiota. Unlike other acidolactic bacteria, Bacillus coagulans is the only one with the property of producing spores during its life cycle, which gives it a special resistance when crossing the gastrointestinal tract, thus reaching the final part of the large intestine practically intact.
Bacillus coagulans creates an environment that improves the absorption of nutrients, reduces digestive problems and helps fight against allergic situations. It has the capacity to produce short chain fatty acids (butyrate, acetate) which are very important for their energy contribution to the intestinal cells and for creating an acid environment that hinders the growth of pathogenic species.
Clinically validated, it has proven to be a safe and effective bacterium in the treatment of diarrhea in individuals with Irritable Bowel Syndrome (1)(2).
It has also been shown that the administration of Bacillus coagulans together with inulin-derived prebiotics reduces abdominal pain and improves constipation in cases of Irritable Bowel Syndrome (3).
It contains Inulin, obtained from Chicory Root, a Prebiotics fiber that reaches the large intestine and promotes the growth of the native or indigenous microbiota.
Manufactured by Align Probiotic, a brand of the American group Procter & Gamble.
Align Probiotic – Digestive Support
Align Probiotic Digestive Support is a supplement that also contains a unique probiotic strain. This is Bifidobacterium infantis 35624. This particular strain is indicated for the treatment of Irritable Bowel Syndrome (IBS) as confirmed by the various studies and clinical trials conducted with this strain (4)(5)
They are chewable tablets, which makes it easier to take them without the need to administer them with a drink. The manufacturer guarantees a minimum concentration of 10 million cfu/tablet throughout the life of the product.
It has a pleasant banana and strawberry flavor and does not have soy or gluten derivatives, which makes it suitable for people with celiac disease.
Manufactured by Align Probiotic, a brand belonging to the US multinational Procter & Gamble and with clinical applications recommended by the Clinical Guide of the Alliance for Education on Probiotics (AEProbio) in both the USA and Canada.
Align Probiotic Supplement – Kombucha – On-The-Go
Probiotic from the well-known brand Align with 1 billion cfu of Lactobacillus acidophilus NCFM and Epicor ®.
Lactobacillus acidophilus NCFM ® one of the most studied strains with proven therapeutic capacity in the treatment of the symptoms of irritable bowel syndrome, diarrhea and constipation (6).
On the other hand, Epicor ® is the registered trademark of a group of metabolites (proteins, antioxidants, polyphenols, polysaccharides, beta-glucans, as well as organic acids and mannans) obtained from the fermentation process carried out by Saccharomyces cerevisiae, a yeast widely used for years in the production of bread as well as in the fermentation of alcoholic beverages such as beer or wine.
Culturelle Probiotic contains 10 billion cfu of one of the most studied and known probiotic species: Lactobacillus rhamnosus GG, with almost 1000 studies and over 200 clinical trials conducted with it. It is a very robust bacterium with great resistance to passage through the gastrointestinal tract.
This strain has multiple therapeutic indications, among them, the prevention of diarrhea associated with antibiotics (7)
On the other hand, this probiotic is also a good option for the reduction of the side effects produced by the treatment for the eradication of Helicobacter Pylori (8)
Highly recommended product, with many and very positive evaluations by its consumers.
Manufactured by the DSM group, a Dutch company with more than 100 years of history and whose last 20 years have been dedicated to nutrition and health solutions.
Each Culturelle Probiotic capsule provides 10 billion cfu of Lactobacillus rhamnosus GG. This product also contains inulin, a Prebiotics fiber extracted from Chicory Root.
These are also gummies for both adults and children over 3 years old that also contain Bacillus coagulans.
Trunature Probiotic contains 2 billion microorganisms from two strains of Bacillus coagulans:
- One of them is Bacillus coagulans MTCC 5856 which is the same strain that LactoSpore ® is composed of (the same one that contains Align Probiotic DualBiotic).
- The other strain is Bacillus subtilis DE111, a strain with therapeutic properties for constipation and diarrhea according to a clinical study conducted on 50 people with intestinal irregularity problems (9).
Just Thrive probiotic Digestive Advantage
Digestive Advantage Probiotic Supplement from the American company Schiff. It contains 500 million cfu of Bacillus coagulans GBI-30.
This strain of Bacillus coagulans GBI-30 has shown therapeutic efficacy in diarrhea associated with irritable bowel disorder, according to a trial conducted with 52 people with this type of pathology and which showed how patients who took the probiotic improved their symptoms compared to those who took a placebo (10)
Another similar study showed a reduction in gastrointestinal discomfort (abdominal pain, flatulence) after meals in patients taking this probiotic compared to those taking a placebo (11)
In addition, Just Thrive probiotic contains lactase, an enzyme that helps hydrolyze the lactose present in most dairy foods and which causes numerous discomforts to all those who are lactose intolerant.
Just Thrive probiotic & antioxidant
Probiotic supplement with 4 strains of bacteria of the same genus Bacillus: Bacillus indicus HU36, Bacillus coagulans SC-208, Bacillus clausii SC-109 and Bacillus subtilis HU58.
These are strains that all have the ability to sporulate, which gives them greater resistance to other probiotics of other genera.
Among the diverse therapeutic activities that we can find in these strains, we can highlight the antioxidant activity thanks to the carotenoids that Bacillus indicus HU36 produces (12) as well as its activity against pathogenic microorganisms thanks to the production of antimicrobial substances that Bacillus subtilis HU58 carries out (13).
On the other hand, Bacillus coagulans SC-208 (1)(2) has shown therapeutic activity against diarrhea caused by Irritable Bowel Syndrome and there is also an aid to the modulation of the immune system thanks to Bacillus clausii SC-109 (14).
Garden of Life Probiotics Primal Defense
Primal Defense is Garden of Life’s line of probiotics based on a blend of microorganisms called Homeostatic® Soil Organisms (HSOs). These are microorganisms that would naturally be present in food if it had not been treated with pesticides, herbicides or other chemicals. These probiotics, which are absent in food, are what supply Garden of Life’s Primal Defense probiotics.
Each Garden of Life Primal Defense capsule contains 5 billion of 13 probiotics from the genera Lactobacillus, Bifidobacterium and Bacillus as well as a common yeast in these products, Saccharomyces boulardii.
Garden of Life Primal Defense helps maintain a balanced intestinal microbiota and a strong, healthy immune system. It thus helps to regulate the intestinal movement and improves the immune system while making us have a better digestion and without discomfort.
It is a product of excellent quality and very well valued by consumers, which will provide an adequate balance of beneficial bacteria against pathogenic microorganisms while creating a healthy intestinal environment.
Garden of Life Raw Probiotics for Women and Men over 50
Two specific Garden of Life Raw Probiotics products designed for men and women over 50 with probiotics, vitamins and digestive enzymes.
Both Garden of Life Raw Probiotics products have a practically similar composition with 85 billion microorganisms from 32 species of beneficial bacteria, among which are 10 species of the genera Lactobacillus and Bifidobacterium and 22 probiotic species derived from kefir that also has this product since in its composition there is also a kefir culture concentrate that is a natural probiotic obtained from fermented milk and with some resemblance to yogurt.
The only difference that exists between them is the amount of some of the minerals that there are in the product since this one varies according to the product for men or for women.
In addition, in the case of the Garden of Life Raw Probiotics formulation for men, the presence of Lactobacillus fermentum stands out, with beneficial properties for maintaining cholesterol within the correct range (15).
In the case of Garden of Life Raw Probiotics for women over 50, the presence of Lactobacillus reuteri and Lactobacillus rhamnosus, two very important probiotic species for women’s vaginal health, stands out. The microbiota is mainly formed by bacteria of the genus Lactobacillus and tends to decrease with age.
In addition to more than 30 probiotics, Garden of Life Raw Probiotics also has 9 vitamins (Vitamin C, D, E and several B group vitamins) with a contribution close to 100% of the daily needs depending on whether you are a man or a woman.
Garden of Life Raw Probiotics also provides essential minerals, Calcium, Iodine, Magnesium, Selenium, Copper, Manganese, Chromium and Molybdenum that are involved in essential processes in our body and that we do not always acquire with our diet.
Finally, to facilitate digestion, the product also has several digestive enzymes such as lactase, which degrades the lactose in milk, or proteases, for the digestion of proteins.
In short, Garden of Life Raw Probiotics is a very complete product because of its great amount of probiotic, vitamins, minerals and digestive enzymes. It has numerous positive evaluations by its consumers and also has the guarantee of Garden Of Life, one of the main manufacturers of probiotic products in the United States.
Garden of Life – RAW Probiotics Ultimate Care
Garden of Life RAW Probiotics Ultimate Care has no less than 100 billion of a total of 34 beneficial bacteria, many of them derived from kefir, making it one of the most powerful probiotics on the market.
These microorganisms included in this product help digestion, promote regularity, support the immune system and help to have an intestinal microbiota balanced with a healthy bacterial population since what this product does is to replace all those bacteria that for various reasons, treatments, medication, age, etc, have been decreasing.
Garden of Life RAW Probiotics Ultimate Care also contains digestive enzymes – proteases – that help digest proteins as well as fruits such as Red Bell Pepper that provide vitamins (including Vitamin A, Vitamin C or Vitamin K) and antioxidants.
Finally, it also contains Green Pea, Carrot, Plum, Cherry, Strawberry and Raspberry which also provide minerals, vitamins and antioxidants.
It is therefore a very complete product, with a large amount of probiotics from more than 30 different species in addition to the contribution of vitamins, antioxidants and minerals.
Garden of Life ensures that in its Raw Probiotics line all its components are kept at low temperature throughout the manufacturing process, storage and transport, so that all its components are kept intact as they have not been degraded by the effect of heat.
Garden of Life RAW Probiotics – Colon Care
Another Raw Probiotics product from Garden of Life with a formula practically the same as the previous one, although in this case the product has half the probiotics, 50 billion instead of 100 of the same probiotic species.
The qualitative composition is practically the same except for the types of digestive enzymes since Garden Of Life Probiotics Colon Care has 17 different digestive enzymes while the previous product only has 3 types of proteases, as the only digestive enzyme.
It also has fruits such as Red Bell Pepper, Green Pea, Carrot, Plum, Cherry, Strawberry and Raspberry, all of which provide vitamins, minerals and antioxidants.
Garden of Life Dr. Formulated Probiotics Fitbiotic – Weight Management– Sticks Packets
Garden of Life Probiotic Supplement with 50 Billion Viable Organisms It is a product specially designed for weight control in people who combine exercise and diet. It is supplied in elongated sachets (sticks).
Like all the products in the Garden of Life Dr. Formulated Probiotics series, it has been created by Dr. David Perlmutter. The formula contains prebiotic fiber that contributes to the feeling of fullness and helps maintain the proper level of blood sugar. The prebiotic fiber also promotes the growth of beneficial bacteria and supports the proper functioning of the digestive system.
The product provides 50 billion microorganisms from 14 different species, as well as 4 g of fiber in each stick.
Product specially designed for those who proactively want to have a weight control.
Garden of Life Dr. Formulated Probiotics Once Daily
Garden of Life’s probiotic supplement, designed and formulated for a healthy microbiota
Contains 30 billion of 14 probiotic microorganisms to take one capsule a day to maintain a healthy immune and digestive system.
It also has two types of prebiotics: Potato Resistant Starch and Acacia Fiber. Prebiotics promote the growth of the microbiota native to the intestine, i.e. the microbiota or intestinal flora that naturally exists, or should exist, in our intestine.
Producto similar al anterior, pero con 25 billones de microorganismos en lugar de los 30 que tiene Garden of Life Dr. Formulated Probiotics Once Daily.
Garden of Life Dr. Formulated Adult Probiotics Once Daily Ultra
In this case, it is a very potent probiotic supplement from Garden of Life as it contains 90 billion of 15 probiotics beneficial to intestinal health.
In this way, the health of the microbiota or intestinal flora and especially the large intestine, specifically the colon, is enhanced. The presence of the Lactobacillus acidophilus NCFM ® strain stands out, a bacterium which, in combination with Bifidobacterium infantis, has shown an improvement in the symptoms (abdominal pain, swelling, diarrhoea, etc.) in patients with Irritable Bowel Syndrome, according to a study carried out with 26 patients with this pathology (6)
Like other probiotics from Garden of Life Dr. Formulated, it contains Potato Resistant Starch and Acacia Fiber, two prebiotics that promote the development of indigenous microbiota in the gut.
Garden of Life Dr. Formulated Probiotics – Urinary Tract
Probiotic supplement specially designed for the prevention of urinary tract infections, especially in women, as this is one of the most common infections of the female gender.
This probiotic is formulated with a compound called Pacran®, a registered trademark of Decas Botanical Synergies, with Cranberry powder that has been shown to be effective in preventing urinary tract infections, since it contains proanthocyanidins, the active component responsible for this antiseptic activity (16).
It has 50 billion of 16 probiotic species, among them Lactobacillus acidophilus NCFM ® and Lactobacillus reuteri, being the latter a very important microorganism due to its presence in the vaginal microbiota.
Probiotic very suitable for women since in addition to its antiseptic activity of the urinary tract, it also contains Vitamin D3, very important for the absorption of calcium and therefore also important in the prevention of osteoporosis.
As with other probiotic products from Garden of Life Dr. Formulated probiotics, it also contains prebiotics, specifically potato Resistant Starch and Acacia fiber. Prebiotics fiber promote the growth of native microbiota in the intestine.
Garden of Life Dr. Formulated Probiotics Prostate
Another Garden of Life probiotics specially designed for men over 45 for its ability to prevent urinary tract disorders and especially those related to benign prostate hyperplasia.
This therapeutic effect is due to the presence of a compound called Fowens® formulated from Cranberry and responsible for this activity, as demonstrated in a clinical study conducted on 124 volunteers with high PSA values (17).
This Garden of Life product also has 50 billion of 15 different probiotic species. Its formula also includes vitamin D3, very important, among other functions, in the absorption of calcium.
Finally, it also has prebiotics fiber, specifically Resistant Starch and Acacia Fiber.
Garden of Life Dr. Formulated Probiotics Mood
Garden of Life Probiotic Supplement with 50 billion of 16 microbial species
In addition to its properties for the rebalancing and balance of the intestinal microbiota, what stands out in this product is the presence of the strains Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 since in a study conducted on 25 volunteers, it was shown that the oral administration of these bacterial strains has beneficial effects for the treatment of psychological problems related to stress which makes it especially indicated in those patients who have a certain tendency to anxiety and depression situations related to stress (18).
On the other hand, it also contains Ashwagandha root. This compound is not a probiotic. It is an herb to which numerous medicinal properties are attributed. One of the best known is its ability to reduce stress (19). It also contains various derivatives of the Blueberry (Vaccinium uliginosum) with antioxidant properties.
Garden of Life Dr. Formulated Probiotics Platinum Series Restore
For situations where an extra supply of probiotics is needed, Garden of Life Probiotics presents this product with no less than 200 billion probiotics.
This product restores and replenishes the lost intestinal microbiota while improving regularity and helping to reduce the digestive problems associated with altered microbiota.
Garden of Life Dr. Formulated Probiotics Platinum Series Immune
Garden of Life Probiotics with 90 billion of 11 different probiotic species
In Garden of Life Probiotics Immune + the presence in the formula of the Lactobacillus acidophilus NCFM®, Lactobacillus rhamnosus GG and Bifidobacterium lactis HN019 strains stands out, all of them very well studied and with very specific therapeutic applications
Lactobacillus rhamnosus GG is perhaps the most studied bacteria and on which more clinical trials have been conducted. It is a bacterium that has been well studied in relation to its activity on the immune system (20).
Lactobacillus acidophilus NCFM®, very studied in the treatment of the symptoms of the irritable bowel syndrome (1)(2) and Bifidobacterium lactis HN019 that improves the transit time through the gut, reduces symptoms of intestinal disorders (constipation, diarrhea, bloating and abdominal pain) (21) and stimulates the cellular response of the immune system (22).
Very similar to this Garden of Life product, there is this other one: Member’s Mark 10 Strain Probiotic with a very similar probiotic formula but with 10 billion microorganisms instead of the 90 billion contained in the Garden of Life Dr. Formulated
Renew Life Probiotic B0042L1S1S B00H61ZBZU B000CMKC5Y – B001LIW11Q (30) y 60 capsules
A product of Renew Life probiotic, a company with more than 25 years in the probiotic supplements sector and which has in its portfolio a series of probiotic supplements of identical formula but different presentations of 15, 30 and 50 billion cfu of beneficial microorganisms.
Renew Life probiotic contains the strains Lactobacillus acidophilus La-14, Lactobacillus plantarum Lp-115, Lactobacillus paracasei Lpc-37 which together with Bifidobacterium lactis Bl-04 have been shown to improve digestive health, with a lower incidence of diarrhea.
Similarly, this group of bacteria provides a rebalancing of the microbiota or intestinal flora with a capacity to modulate the immune system and reduce the incidence of bacterial vaginosis in women (23).
It also includes Bifidobacterium lactis HN019 that improves gastrointestinal transit in patients with constipation problems (21).
The formula also contains Bifidobacterium lactis Bi-07 and Lactobacillus acidophilus NCFM® a combination that supports the immune system. In a study of 465 people, this combination of probiotics was shown to have an effect on the incidence of colds, so people taking these two bacteria had a lower incidence than those taking a placebo. There was also a lower incidence of upper respiratory tract infections (24).
Also noteworthy is the presence of Lactobacillus rhamnosus GG, a much studied strain and, as we have already mentioned when discussing Culturelle probiotics, it is a very robust probiotic with therapeutic capacity in the treatment of diarrhea associated with antibiotics, as well as for treating the side effects produced during the treatment of eradication of Helicobacter pylori (7).
Nature’s Way Fortify Extra Strength
Probiotic from the American company Nature’s Way with a formula practically the same as those we have just seen from Renew Life Probiotics.
It therefore has a similar therapeutic activity in terms of its function to maintain the balance of the microbiota or intestinal flora (23)(24), improve problems of constipation (21) and its action on the immune system.
Nature’s Way – Fortify Optima probiotic
Another probiotic from the American company Nature’s Way. Eight probiotic strains from the company, also American, Danisco (Dupont), which always offers probiotics of proven quality and with numerous clinical trials that guarantee their efficacy.
Fortify Optima has 50 billion probiotic species and is therefore one of the probiotics on the market with the largest number of beneficial bacteria. Among them are two strains of the same species of Bifobacterium lactis: One of them, Bifidobacterium lactis Bl-04 ® which stands out for its therapeutic efficacy in allergic processes such as hay fever, and the other, Bifidobacterium lactis Bl-07 ® which has the ability to modulate the immune system and combat digestive discomfort by stabilizing the intestinal microbiota, and more obviously, discomfort that is due to treatment with antibiotics.
On the other hand we have two strains of the same species of Lactobacillus acidophilus, one of them, Lactobacillus. acidophilus NCFM® that together with Bifidobacterium infantis has shown its efficacy in the treatment of the symptoms of irritable bowel syndrome (6) and Lactobacillus acidophilus La-14, a well studied strain, very resistant to gastrointestinal conditions (acid and bile) and with great capacity of adhesion to epithelial cells that prevent the proliferation of pathogenic species.
Regarding to this Probiotic Supplement, it is necessary to clarify that this product currently sold as VSL#3 is NOT the original formula invented by Dr. Simone and marketed for several years, until 2016, under the same name VSL#3.
The original formula of VSL#3, Dr Simone’s, is currently marketed under the brands Visbiome (in the USA) and Vivomixx (in Europe).
The current formula of VSL#3 is very similar to Dr Simone’s original formula. It is composed of the same 8 species (Streptococcus thermophiles, Bifidobacterium breve, Bifidobacterium longum – reclassified as B. lactis -, Bifidobacterium infantis -reclassified as B. lactis-, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus delbrueckii subsp. bulgaricus -reclassified as L. helveticus- ) and also has the same amount of microorganisms, 112.5 billion CFU, but it is not really the same formula since the strains are not the same and in fact VSL#3 does not declare them, unlike Visbiome which does.
No clinical trials could be located with this new VSL#3. All information in this regard is based on the original formula, although the manufacturer of the product, on its website, states the therapeutic activity of the product for the treatment of Irritable Bowel Syndrome and Ulcerative Colitis.
Visbiome contains the original formula of the product marketed until 2016 under the name VSL#3.
It is the original formula that Dr Simone created and contains the same 8 specific strains of each of the species that make up the formula and that are the ones that were part of the original formula: Lactobacillus paracasei DSM 24733/SD5218, Lactobacillus plantarum DSM 24730/SD5209, Lactobacillus acidophilus DSM 24735/SD5212, Lactobacillus delbrueckii subspecies bulgaricus (Reclassified as Lactobacillus helveticus) DSM 24734/SD5210, Bifidobacterium longum (Reeclassified as Bifidobacterium lactis) DSM 24736/SD5220, Bifidobacterium infantis (Reeclassified as Bifidobacterium lactis) DSM 24737/SD5219, Bifidobacterium breve DSM 24732/SD5206, Streptococcus thermophilus DSM 24731/SD5207.
Each capsule of Visbiome Visbiome Probiotic has 112.5 billion cfu of the 8 probiotic strains mentioned
Visbiome has shown therapeutic activity in the treatment of diarrhea in children caused by rotavirus (24), as well as in diarrhea associated with antibiotics (25) and in the symptoms of irritable bowel syndrome such as diarrhea (26) and bloating (27)
Also noteworthy is its use for remission of ulcerative colitis as demonstrated in a clinical trial conducted on 34 patients with this pathology (28).
Florastor Probiotic Capsules
Florastor is a probiotic supplement with a single species, Saccharomyces boulardii lyo CNCM I-745. It is a healthy yeast for the gut and therefore balances the intestinal microbiota.
The Saccharomyces boulardii lyo CNCM I-745 yeast is indicated for various pathologies that produce diarrhea, associated with antibiotics (29), traveler’s diarrhea (30)(31), as well as in the diarrhea produced by Clostridium difficile (32).
Saccharomyces boulardii lyo CNCM I-745 improves digestion by increasing the activity of digestive enzymes and improving digestive problems due to enzyme deficiency. Also, patients with diarrhea benefit from this probiotic due to improved enzyme activity and osmotic effects that make the stools less liquid (33).
It has also shown its efficacy as a treatment for the eradication of Helicobacter Pilory (34).
Nature’s way Pearls Probiotic
Pearls Probiotic is another product of Nature’s way, an American company with more than 50 years in the natural health products market and with a wide range of products.
Nature’s way Pearls Probiotic is one of the most highly rated and best valued products. Unlike other manufacturers, all of the probiotics in this product are registered strains from world-renowned collections.
Each capsule (pearl) has 1 billion viable bacteria from a total of 6 probiotic strains, 2 lactobacilli (Lactobacillus acidophilus NCFM® and Lactobacillus rhamnosus Lr-32) and 4 bifidobacteria (Bifidobacterium lactis Bl-04®, Bifidobacterium longum BB536, Bifidobacterium breve M-16V and Bifidobacterium bifidum bb-02). All of these are very common probiotic bacteria in intestinal probiotics to maintain proper intestinal health and care of the colon, the end part of the large intestine, as well as probiotics that also strengthen the immune system.
The exclusive formula of Probiotic Pearls includes a capsule with a special coating that makes it more resistant to the acidic environment of the stomach and bile, thus ensuring that the microorganisms reach the intestine without being previously degraded.
Bifidobacterium breve M-16V has been tested in several thousand children with numerous studies, where it has been seen how this microorganism stimulates the increase of bifidobacteria in their intestine.
Bifidobacterium lactis Bl-04 has been widely studied for its therapeutic effect on immunity and allergies, as well as diarrhea associated with antibiotics.
Lactobacillus acidophilus NCFM® is one of the most studied probiotic strains in vitro and with more clinical trials in both humans and animals, being one of the best probiotics today. It has enormous potential to strengthen general health and gastrointestinal health in particular, as well as to boost immune function and reduce the disruption caused by antibiotic intake and irritable bowel symptoms.
Nature’s way Pearls Probiotic – For the over 50’s
Nature’s way Pearls Probiotic – For the over 50’s it is focused on an older patient where the presence of bifidobacteria declines over the years.
To this end, Nature’s Way offers Pearls Adult 50+ with 1 billion 5 bifidobacteria: Bifidobacterium longum BB536, Bifidobacterium breve M-16V, Bifidobacterium lactis Bl-04 ®, Bifidobacterium infantis M-63, Bifidobacterium bifidum Bb-02.
Bifidobacteria intake helps return the proper level of bifidobacteria to the intestine, which decreases as we age. In addition, daily consumption protects against occasional bloating, constipation, and digestive discomfort. It helps to have more regularity, immunity and health in the colon.
The product is supplied in capsules (pearls) which, like the previous product, also has a triple layer that gives it greater resistance to passage through the gastrointestinal tract.
Nature’s way Pearls Probiotics – Immune – Regularity & Immunity
Another Nature’s Way probiotic. As is customary with this brand, it always identifies not only the species but also the strain which also denotes a product quality that is not always available from competitors.
In this case it is a probiotic with 1 billion bacteria from 4 strains: 2 Lactobacillus (L. plantarum LP-115 and L. acidophilus NCFM®) and 2 Bifidobacterium (B. lactis BI-04 and B. longum BB536).
The strains used by Nature’s Way in this product are from prestigious companies such as the American Danisco (Dupont) or the Japanese Morinaga Milk.
L. acidophilus NCFM® is one of the most studied strains with proven therapeutic ability in treating the symptoms of irritable bowel syndrome, diarrhea, and constipation (6).
In a 2007 study, L. plantarum LP-115 showed an ability to increase the immune response with increased IgG (35).
In another study, in this case in a combination with B. lactis BI-04 and L. acidophilus NCFM® showed to reduce the symptomatology in the case of birch pollen allergy (36).
B. longum BB536 is the strain registered by the Japanese company Morinaga Milk. Although it is not well known among the probiotic products we usually find on the market, it is a clinically documented bacterium with healthy effects for the body by modulating the microbiota, improving intestinal health and alleviating allergic disorders (37).
A differentiating characteristic of this product is the presence of Lactoferrin, a protein present in breast milk which has, among other properties, the protection of the organism against infections playing a fundamental role in the immune response (38).
Nutrition Essentials Probiotic – 900 Billion CFU
Symbiotic Probiotic Supplement from Nutrition Essentials with a probiotic species: bacillus coagulans 15 B and a prebiotic fiber, FOS (Fructooligosaccharides).
This is one of the best selling products on the internet with almost 20,000 positive comments from its consumers.
It is a product that also has a much higher probiotic load than the rest, since it has no less than 900 billion CFU’s of Bacillus coagulans,
Among its properties, improve symptoms of irritable bowel syndrome in both children (39) and adults (40).
It is also effective in treating women who are on antibiotics for bacterial vaginosis (41) as well as patients with acute diarrhea (42) and for treating constipation (43).
Healthy Origins Probiotic
Probiotic from Healthy Origins, an American company with a wide range of health products.
Healthy Origin Probiotic has 30 billion of 8 strains of the genera Lactobacillus and Bifidobacterium: L. acidophilus La-14, B. lactis Bl-04, L. salivarius Ls-33, L. plantarum Lp-115, B. longum Bl-05, L. rhamnosus Lr-32, B. breve Bb-03 and L. casei Lc-11.
The 8 strains are correctly identified, something that not all manufacturers do, and are from the firm Danisco (Dupont) one of the most internationally recognized probiotic producers.
Among their beneficial properties, the capacity of resistance to stomach acid and bile, the inhibition of growth of pathogenic microorganisms and the modulation of the immune system stand out.
They are also strains with a long history of use, which makes the product safer.
It is therefore a product that has all the guarantees of recognized strains and with clinical studies that demonstrate its therapeutic effectiveness.
Best Naturals Probiotic
A similar product to the previous one, also manufactured in the United States and with 30 billion of 10 probiotic strains, also from the firm Danisco (Dupont). The difference lies in some different species between the two products, although the effects are similar since they are lactic acid bacteria and bifidobacteria.
They are very common probiotic species among the probiotic products that include the two species contained in yogurt (Lactobacillus bulgaricus and Streptococcus thermophilus).
This product also has Lactococcus lactis, a microorganism isolated from kefir with probiotic properties, but not as well known as those of other acidolactic species.
SBO Probiotic + Organic Greens
Another probiotic with Bacillus coagulans in which we must highlight the presence of Organic Greens Blend containing Spirulina (spirulina platensis), Broccoli, Spinach and Kale. They are all derived from vegetables that provide a high amount of vitamins and minerals.
It also has amylase, an enzyme that helps in the metabolism of the polysaccharides (sugars) of the fibers and starch.
Nature’s Bounty Probiotic Ultra Strength
A very complete probiotic supplement, similar to Renew Life Probiotic as some of the strains it contains are exactly the same: Lactobacillus acidophilus La-14, Lactobacillus paracasei Lpc-37 and Bifidobacterium lactis Bl-04. It also has the same species of Lactobacillus plantarum, although in this case it is the 299v strain with therapeutic effects for diarrhea (44)(45).
Similarly, Lactobacillus plantarum 299v strain is recommended for the treatment of symptoms of Irritable Bowel Syndrome (IBS), as confirmed by studies (46)(47(48).
In addition, Nature’s Bounty probiotic is formulated with Lactobacillus paracasei DSM 13434 and Lactobacillus plantarum DSM 15312, with studies showing their therapeutic efficacy in reducing the risk of getting the common cold (49).
It is also worth mentioning the presence of Lactobacillus bulgaricus Lb-87, which is one of the species that together with Streptococcus thermophilus are part of yogurt, with great capacity of adhesion to the intestinal wall, thus inhibiting colonization by pathogenic bacteria. This last characteristic is also present in Lactobacillus salivarius Ls-33 and Lactobacillus casei Lc-11, two other probiotics present in the formula of this Nature’s Bounty probiotic
Dr. Mercola Probiotic – Complete Spore Restore
Dr Mercola is a well-known American brand of supplements founded by Dr Joseph Mercola.
Dr Mercola Probiotic Complete Restore contains 4 billion of the strains Bacillus coagulans SC-208 (1)(2) and Bacillus clausii SC-109 (14), being the SC-208 strain effective against the symptoms of diarrhea due to irritable bowel and the SC-109 strain, for its ability to modulate the immune system as we have already discussed.
This product has as a differentiating element a Dr. Mercola’s Organic Mushroom Blend composed of Lion’s Mane (Hericium erinaceus) with antioxidant capacity (50), Shiitake (Lentinus edodes) with therapeutic activity to strengthen the immune system (51) and Turkey Tail (Trametes versicolor) also with antioxidant capacity due to the presence of flavonoids and phenolic derivatives (52).
Dr. Mercola Complete Probiotics
Dr. Mercola Complete Probiotic containing 70 billion of 10 species of probiotics: Lactobacillus acidophilus DDS®-1, Lactobacillus casei, Lactobacillus plantarum, Lactobacillus salivarius, Lactobacillus rhamnosus, Lactobacillus brevis, Bifidobacterium lactis, Bifidobacterium longum, Bifidobacterium bifidum, Streptococcus thermophilus.
It is one of the probiotics with the highest concentration of beneficial bacteria for the organism (70 billion) in addition to being a common species in this type of probiotic products.
Among all of them, the Lactobacillus acidophilus DDS®-1 strain stands out, as this is a strain from UAS Lab LLC, a company with more than 35 years in the field of probiotics, and which has been studied in clinical trials in both animals and humans.
Among the beneficial effects of this Lactobacillus acidophilus DDS®-1 strain, we have:
- Reduces the duration of respiratory infections as demonstrated in a study of 225 children (53).
- Production capacity of acidophilin, an anti-pathogenic substance avoiding being colonized by “bad” bacteria.
- Reduces symptoms of lactose intolerance, diarrhea, vomiting and cramping (54).
- In combination with species of the genus Bifidobacterium, it improves the symptoms of Irritable Bowel Syndrome (55).
- Prevention of Traveler’s Diarrhea
- It is also a strain capable of surviving passage through the gastrointestinal tract and modulating intestinal microbiota.
American Health Probiotic – Acidophilus and Bifidum B01AJR1K9S
Probiotic manufactured in the United States. It has two probiotic strains, Lactobacillus acidophilus La-14 and Bifidobacterium bifidum SD-5857. Both originate from companies of recognized reputation in the manufacture of probiotics (Danisco – Dupont and Probio USA Inc) which gives it a plus in quality compared to other manufacturers who do not mention their origin.
They are strains with a long history of safe use, which have demonstrated their ability to resist the acidic conditions of the stomach and as well as bile and good intestinal adhesion preventing the proliferation of pathogenic organisms. They also have a capacity to modulate the immune system by increasing its response.
It is easily taken, since they are chewable tablets that each have 1 billion probiotic species.
New Chapter Probiotic
Symbiotic that provides 5 billion cfu of the Lactobacillus plantarum LP01 and Bifidobacterium breve BR03 strains. These two strains improve the problems of irregularity as well as hard stools, according to a clinical study conducted with 300 patients (56).
They also improve symptoms related to irritable bowel syndrome according to a clinical study conducted in 70 IBS patients (57).
It also provides another 5 billion Saccharomyces boulardii, the only yeast considered probiotic capable of adhering to pathogenic bacteria such as Escherichia coli or Salmonella, preventing them from colonizing the digestive system. It creates a hostile environment for pathogenic microorganisms through the synthesis of some acids derived from capric and caproic acid.
Andrew Lessman Probiotic
Probiotic from the brand Andrew Lessman, name of the founder of ProCaps, an American company dedicated to probiotic supplements and vitamins (Andrew Lessman vitamins) for more than 30 years.
It is a mixture of 4 beneficial probiotic bacteria for our organism. Among them, we can highlight the strains Bifidobacterium lactis HN019 and Bifidobacterium lactis BL-04. We can find in the market both presentations of 10 billion and 25 billion beneficial bacteria.
As it has been already commented in other products containing Bifidobacterium lactis HN019, it is a microorganism that improves the gastrointestinal transit in patients with constipation problems (21).
Bifidobacterium lactis Bl-04, on the other hand, stimulates the immune system. In a study of 115 people, prior administration of Bifidobacterium lactis Bl-04 was shown to reduce the incidence of respiratory infection in the group taking the probiotic compared to the group taking the placebo (58).
It also contains the strains Lactobacillus acidophilus La-14, Lactobacillus plantarum Lp-115, Lactobacillus paracasei Lpc-37 that together with Bifidobacterium lactis Bl-04 have been shown to improve digestive health, a lower incidence of diarrhea, modulation of the immune system and a lower incidence of bacterial vaginosis in women while providing a rebalancing of the microbiota or intestinal flora (23).
TruBiotics Daily Probiotic
Probiotic supplement from the well-known German laboratory Bayer. It has 2 billion CFUs of one of the most studied probiotic strain combinations: Lactobacillus acidophilus LA-5 and Bifidobacterium animalis BB-12.
This combination of probiotic microorganisms has shown numerous therapeutic effects in the treatment of traveler’s diarrhea (59), constipation (60) as well as in accelerating the recovery of the microbiota or intestinal flora after treatment with antibiotics (61).
Thorne Research FloraSport Probiotic Supplement
Probiotic supplement with a premix called Howaru® Restore made up of these 4 probiotic strains Lactobacillus acidophilus NCFM®, Lactobacillus paracasei Lpc-37™, Bifidobacterium lactis Bi-07™ and B Bifidobacterium lactis Bl-04™ and of which Thorne Research FloraSport contains a total of 20 billion.
These 4 strains have been shown to have excellent therapeutic efficacy in patients with diarrhea due to antibiotics, reducing the number of episodes, shorter duration of the diarrhea and less liquid stools as well as a reduction in symptoms associated with diarrhea such as fever, abdominal pain and bloating (77).
Genestra Brands – HMF Travel – Gastrointestinal Health When Travelling
Genestra Probiotic contains a mixture of 35 billion of the strains Lactobacillus acidophilus (CUL-60), Lactobacillus acidophilus (CUL-21), Bifidobacterium bifidum (CUL-20), Bifidobacterium animalis subsp. lactis (CUL-34) as well as the yeast Saccharomyces boulardii lyo CNCM I-745 which is indicated for various situations that produce diarrhea, such as traveler’s diarrhea (30)(31)
As for the 4 strains of Bifidbacterium and Lactobacillus, during the last 15 years, 10 clinical studies have been carried out with this combination of strains that endorse its beneficial properties in adults, children and babies in digestive and immune health and even in mood.
There are studies that show its therapeutic benefits in gastrointestinal disorders (24)(25).
Probiotic from the company Hyperbiotics with 5 billion of 15 probiotic species of the genera Lactobacillus and Bifidobacterium. (Lactobacillus plantarum, L. fermentum, L. acidophilus, Bifidobacterium infantis, L. casei, B. longum, L. rhamnosus, B. lactis, L. reuteri, L. salivarius, L. paracasei, L. gasseri, B. bifidum, B. breve and Streptococcus thermophilus) which are some of the most common species and have benefits at the intestinal level, improving digestive processes and strengthening the immune system.
What differentiates this product from the rest of the competition is the use of BIO-tract®, a technology patented by Probi USA Inc. and which, according to the manufacturer, confers resistance to probiotics when they pass through the gastrointestinal tract, resisting the very acidic pH of the stomach and thus guaranteeing that they reach the intestine alive and intact, which is where they carry out their function.
With this BIO-tract®, Hyperbiotics claims to have 15 times more survival of microorganisms than competing probiotics using standard capsules.
Hyperbiotic is a North American company, based in Nevada. It has a wide range of health supplement products.
Vitamin Bounty Pro 50 Probiotic with Prebiotics
Symbiotic that provides 50 billion cfu of the genera Lactobacillus and Bifidobacterium as well as the yeast Saccharomyces boulardii.
It also contains several types of fiber that act as a prebiotic, promoting the growth of microbiota native: Hordeum vulgaris, oat sativa (this one even with properties to lower cholesterol level 62, Triticum aestivum, and Alfalfa (the latter also with properties to lower cholesterol) 63
Vitamin Bounty Pro 50 Probiotic has several thousand positive comments from its consumers.
Flora Advanced Adult Probiotic
Probiotic with 34 billion microorganisms of the genera Lactobacillus and Bifidobacterium.
These are strains of the Canadian company Lallemand Inc, with almost 100 years dedicated to the development of bacteria, yeasts and probiotics.
There is not much published information about these strains in particular, although there are some studies that show that the strains Bifidobacterium bifidum HA-132, Bifidobacterium breve HA-129, Bifidobacterium longum HA-135, Lactobacillus acidophilus HA-122 and Lactobacillus plantarum HA-119 are able to rebalance the microbiota in elderly patients who take a diet rich in protein as a result of sarcopenia they suffer due to age (64)
However, the species contained in this product are common in intestinal probiotics and therefore exert their function of rebalancing the microbiota when it is altered by some treatment (e.g. treatment with antibiotics)
Solgar Probiotics – Acidophilus 40+ Plus
Solgar is an American company with recognized prestige in the field of nutritional supplements for over 70 years. It has a portfolio with all kinds of products for health care.
Each capsule of Solgar Acidophilus 40+ has 1.5 billion microorganisms of the probiotic species Lactobacillus acidophilus LA-5, Lactobacillus paracasei (L.CASEI 431), Lactobacillus rhamnosus GG, Bifidobacterium lactis BB-12 and Streptococcus thermophilus TH-4. Unlike other brands and manufacturers, Solgar declares in its labelling the specific strain of each species. This is also the case of registered strains from prestigious collections such as Chr. Hansen and Valio Ltd.
Among the benefits identified in these strains we have L. acidophilus LA-5 and B. lactis BB-12, which are two strains that have generally been studied together given the symbiosis that exists between them, as well as being very safe and with very good tolerance and no adverse effects. The combination of L. acidophilus LA-5 and B. lactis BB-12 has been shown to improve constipation in elderly patients (65).
In the case of children, the administration of L. rhamnosus GG together with the combination of L. acidophilus LA-5 and B. lactis BB-12 managed to normalize the microbiota more quickly after treatment with antibiotics (66).
Regarding L. CASEI 431 ®, it is one of the strains with more studies. It is related to a better immune response before symptoms of respiratory infections reducing their duration (67).
Finally, Streptococcus thermophilus TH-4 is one of only two species recognized as part of yogurt. It is associated with improved gastrointestinal function, reducing discomfort, and especially when administered along with B lactis BB-12 as in this case.
Solgar Probiotics Multi-Billion Dophilus
Product also manufactured by Solgar and very similar to the previous one from the qualitative point of view since the 4 strains that it has are exactly the same that we have seen in the previous product and coming from the same collections.
The main difference is the absence of Streptococcus thermophilus TH-4 and, from a quantitative point of view, that we are facing a product with 5 billion microorganisms per dose, more than 3 times the dose of the previous product. The absence of S. thermophilus takes away the plus that this microorganism has in the treatment of diarrhea, but in exchange it is compensated with a greater concentration of the rest of microorganisms.
Solgar Probiotic Probi 20 billion
Solgar Probi ® contains in its formula 20 billion ufc of a single probiotic strain: Lactobacillus plantarum 299v. Numerous studies have been carried out on this strain that confirm its therapeutic capacity and indication for the treatment of diarrhea as well as for the symptoms of Irritable Bowel Syndrome (IBS).
According to the Alliance for Education on Probiotics (AEProbio) of the United States and Canada, this is a strain for which studies have confirmed its indication for the treatment of diarrhea (44)(45)
Similarly, the Lactobacillus plantarum 299v strain is recommended for the treatment of Irritable Bowel Syndrome (IBS) symptoms, as confirmed by studies (46)(47)(48)
Now Probiotic 10
Product with 10 probiotic species. All of them are strains from the firm Danisco, dedicated to health supplements and belonging to the Dupont group, one of the largest North American industrial groups.
It is composed of 6 lactobacilli: Lactobacillus acidophilus La-14, Lactobacillus plantarum Lp-115, Lactobacillus casei Lc-11, Lactobacillus paracasei Lpc-37, Lactobacillus rhamnosus Lr-32 and Lactobacillus salivarius Ls-33 together with 3 bifidobacteria: Bifidobacterium lactis Bl-04, Bifidobacterium breve Bb-03 and Bifidobacterium longum BI-05 and a streptococcus, Streptococcus thermophilus St-21.
In addition to the beneficial effects of bifidobacteria for the rebalancing of the gastrointestinal tract, a study conducted in 2019 revealed how the strains L. paracasei Lpc-37, B. lactis Bl-04, L. acidophilus La-14, and L. plantarum Lp-115 show an ability to improve intestinal health, reducing the negative effects of antibiotic intake, diarrhea, as well as a modulation and rebalancing of intestinal microbiota (23).
S. thermophilus acts in the same way (68), being also one of the only two species that are part of the authentic yogurt.
The product has several presentations: 25, 50 and 100 billion cells of the same probiotic microorganisms and with excellent positive comments from consumers.
Now Probiotic 10 & Bifido Boost
In this case, it is the same product as the previous one, with the same 10 probiotic strains and 25 billion viable microorganisms.
The difference of this product with respect to the previous one is its content is a special prebiotic based on xylose, a xyloligosaccharide obtained from corn. It is a prebiotic patented by AIDP Inc. under the name PRETICX™ XOS and recently authorized by both the FDA (GRAS Status) and the European EFSA.
The theory behind this prebiotic PRETICX™ XOS is its ability to stimulate the growth of certain species of bifidobacteria present in the body in a native way and hence the product is called “Bifido Boost”.
Inessa Probiotic – Lactobacillus Rhamnosus GG
Product with a single probiotic: Lactobacillus rhamnosus GG. It is important to note that this particular strain (GG) is the one on which most studies (about 1000) and clinical trials (about 200) have been conducted. It is a robust strain, stimulates the proliferation of intestinal epithelial cells and secretes antimicrobial substances such as mucins that prevent the proliferation of pathogens. It strengthens the immune system and has very positive effects on digestion as well as on the treatment of diarrhea (68)(69).
It also has L-Glutamine, one of the essential amino acids very important as a source of intestinal energy and with a very important role in the functioning of the Tight Junctions of the intestinal cells that allow having the correct intestinal permeability (70).
Unlike other products, this one does not contain any type of prebiotic which avoids possible intolerance problems that can occur and is also suitable for those people who are following a low fiber diet, such as the low FODMAP diet (Low Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyol).
It has a total of 10 billion cfu of Lactobacillus rhamnosus GG.
It is a good choice as a probiotic since its composition has been widely studied and verified. The product is manufactured by Inessa, a British company with more than 10 years dedicated to health care products and with very good evaluations by its consumers.
Olympian Labs Probiotic
Probiotic from the American company Olympian Labs. It has several probiotic products in its portfolio.
In the case of Complete Prebiotic & Probiotic, the product contains 25 billion 8 strains of the genera Lactobacillus and Bifidobacterium. The strains used in this product originate from the Canadian company Lallemand Health Solution, founded almost 100 years ago and consolidated internationally as a manufacturer of probiotics.
Although the product has the guarantee of having strains of recognized origin, we cannot specify certain therapeutic activities and clinical applications of these strains since it has not been possible to find publications of research or clinical trials carried out with these Lallemand strains that allow us to state for which particular pathology one or another strain is recommended.
Like other similar products, it also has FOS, a fructooligosaccharide that acts as a prebiotic fiber.
Balance Probiotic – Vital Concept
Balance is another very complete probiotic product as it contains 11 species of the genera Lactobacillus and Bifidobacterium that we usually find in these probiotic supplements.
As with other manufacturers, only the species of the probiotic is indicated but not its strain, so it is not possible to establish a direct relationship between clinical trials carried out with the probiotics included in Balance and their specific therapeutic effect.
In any case, they are lactobacilli and bifidobacteria that help to rebalance the intestinal microbiota with all the positive effects that they bring: better digestion, absence or treatment of diarrhea and all the other benefits already mentioned that probiotics bring.
This Balance product is manufactured in Germany and has been well evaluated by its consumers.
Probiotic with 10 billion cfu of 4 microorganisms: Bacillus subtilis DE111, Lactobacillus plantarum, Lactobacillus acidophilus and Lactobacillus rhamnosus. As we have already commented before, the Bacillus subtilis DE111 strain has therapeutic activity for cases of diarrhea and constipation (9).
The presence in the formula of both Vitamin C, a powerful antioxidant, and Vitamin D3, very important for its involvement in calcium absorption, is noteworthy.
It also contains Zinc, a mineral that intervenes in numerous metabolic processes as well as Echinacea purpurea, a plant used for the treatment of the common cold due to its immune system enhancing characteristics.
Phillips Colon Health Probiotic
Probiotic supplement of the Phillips brand, with almost 100 years of experience in the world of digestive health and belonging to the German multinational Bayer.
It is a probiotic with 1.5 billion viable cells from 3 strains of microorganisms: Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1 and Bifidobacterium longum MM-2.
One of the characteristics of this product is its therapeutic activity against the symptoms of seasonal allergies, according to a clinical study carried out with 173 people who were given these three probiotic strains or a placebo. The group that took the probiotics improved their symptoms compared to those who took the placebo (76).
Independently of this therapeutic activity against the symptoms of seasonal allergies, the strains contained in the product are part of our intestinal microbiota, so its intake also promotes a balance of the intestinal flora thus eliminating alterations such as constipation, diarrhea or bloating.
Physician’s choice Probiotic 60 Billion CFU
Perhaps the best-selling probiotic, with over 27000 very positive ratings for the product
60 billion Bifidobacterium and Lactobacillus but with an additional mix of prebiotics, based on Jerusalem Artichoke root, which contains inulin, a very common prebiotic that stimulates the growth of the native flora, Acacia Senegal, which provides gum acacia with a lot of fiber as well as Chicory root, another prebiotic fiber component that together with the other two, promotes the growth of the native microbiota.
Solimo Amazon Brand Probiotic
Probiotic with 10 billion cfu of a single strain: Lactobacillus acidophilus La-14, registered by the prestigious company Danisco.
This strain Lactobacillus acidophilus La-14, has been well studied. It is very resistant to gastrointestinal conditions (acid and bile) and has a great capacity to adhere to the epithelial cells that prevent the proliferation of pathogenic species.
It is a very simple probiotic and one of the most economical that can be found in internet stores.
PB 8 Probiotic
PB8 probiotic contains 14 billion of 8 of the most common beneficial species of Lactobacillus and Bifidobacterium
It does not specify the strain of origin, so it is not possible to attribute any particular clinical trial to it, although, based on the species it contains, it is a good probiotic for rebalancing the intestinal microbiota.
It is economical and has received many positive comments in online stores.
Klaire Labs Probiotic
Klaire Labs probiotic has in its portfolio the product Ther-Biotic Complete, a supplement with 25 billion of 12 species of bacteria of the genera Lactobacillus and Bifidobacterium.
These are species of bacteria that are common in the human gut, although the strain of each is not specified, so it cannot be linked to specific clinical studies.
The opinions of consumers are very favorable, with a high number of positive evaluations.